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Massimo Pandolfo Selected Research

Friedreich Ataxia (Friedreich's Ataxia)

1/2022DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.
1/2021Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 4-year cohort study.
1/2020Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.
1/2019Protocol of a randomized, double-blind, placebo-controlled, parallel-group, multicentre study of the efficacy and safety of nicotinamide in patients with Friedreich ataxia (NICOFA).
10/2018Automated functional upper limb evaluation of patients with Friedreich ataxia using serious games rehabilitation exercises.
9/2017Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivo.
11/2016Friedreich ataxia-induced pluripotent stem cell-derived neurons show a cellular phenotype that is corrected by a benzamide HDAC inhibitor.
8/2016Pharmacological treatments for Friedreich ataxia.
2/2015Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data.
10/2014Deferiprone in Friedreich ataxia: a 6-month randomized controlled trial.
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Massimo Pandolfo Research Topics

Disease

35Friedreich Ataxia (Friedreich's Ataxia)
01/2022 - 02/2002
17Ataxia (Dyssynergia)
01/2021 - 08/2004
10Neurodegenerative Diseases (Neurodegenerative Disease)
09/2017 - 04/2004
10Spinocerebellar Ataxias (Spinocerebellar Ataxia)
12/2016 - 09/2007
5Epilepsy (Aura)
03/2014 - 11/2003
4Mitochondrial Diseases (Mitochondrial Disease)
01/2020 - 11/2002
4Cerebellar Ataxia (Dysmetria)
12/2017 - 06/2007
3Disease Progression
09/2017 - 10/2014
2Temporal Lobe Epilepsy
10/2013 - 04/2012
2Seizures (Absence Seizure)
10/2013 - 11/2006
2Neoplasms (Cancer)
11/2012 - 12/2004
2Fibrosis (Cirrhosis)
04/2012 - 01/2003
2Hypersensitivity (Allergy)
03/2012 - 03/2011
2Atrophy
08/2011 - 03/2004
2Cardiomyopathies (Cardiomyopathy)
07/2009 - 01/2003
2Atherosclerosis
08/2008 - 10/2007
1Multiple Sclerosis
04/2017
1Dystonia (Limb Dystonia)
03/2017
1Neuroferritinopathy
03/2017
1Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)
03/2017
1Polyneuropathies (Polyneuropathy)
10/2016
1Rare Diseases (Rare Disease)
04/2015
1Neutropenia
10/2014
1Agranulocytosis (Granulocytopenia)
10/2014
1Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
09/2014
1Headache (Headaches)
03/2014
1Migraine Disorders (Migraine)
03/2014
1Infections
01/2014
1Fibromuscular Dysplasia
01/2014
1Neck Pain (Cervicalgia)
01/2014
1Hippocampal Sclerosis
10/2013
1Epileptic Syndromes
10/2013
1Spinocerebellar Degenerations (Marinesco Sjogren Syndrome)
10/2013
1Febrile Seizures (Febrile Seizure)
10/2013
1Glioma (Gliomas)
10/2013
1Carcinogenesis
11/2012
1Alzheimer Disease (Alzheimer's Disease)
04/2012
1Schizophrenia (Dementia Praecox)
04/2012
1Necrosis
04/2012
1Drug-Related Side Effects and Adverse Reactions
03/2012
1Exanthema (Rash)
03/2011
1Stevens-Johnson Syndrome (Lyell's Syndrome)
03/2011
1Uniparental Disomy
03/2011
1Spastic ataxia Charlevoix-Saguenay type
03/2011
1Insulin Resistance
07/2009

Drug/Important Bio-Agent (IBA)

22FrataxinIBA
01/2022 - 02/2002
8Biomarkers (Surrogate Marker)IBA
12/2017 - 01/2010
6Mitochondrial Proteins (Mitochondrial Protein)IBA
01/2022 - 11/2002
6IronIBA
01/2020 - 11/2002
5indium arsenide (InAs)IBA
09/2018 - 03/2012
5Histone Deacetylase InhibitorsIBA
11/2016 - 04/2008
5AntioxidantsIBA
08/2016 - 02/2008
5idebenoneIBA
08/2016 - 03/2009
5polyglutamineIBA
09/2014 - 03/2006
4Pharmaceutical PreparationsIBA
10/2013 - 02/2008
3DNA (Deoxyribonucleic Acid)IBA
10/2016 - 03/2011
3Biological ProductsIBA
02/2015 - 10/2013
3Ataxin-1IBA
09/2013 - 09/2007
3Proteins (Proteins, Gene)FDA Link
11/2011 - 09/2007
3EnzymesIBA
04/2010 - 12/2004
2Protein Isoforms (Isoforms)IBA
01/2022 - 01/2007
2SulfurIBA
01/2020 - 08/2013
2DeferiproneIBA
10/2014 - 08/2013
2HLA-A Antigens (HLA-A)IBA
03/2012 - 03/2011
2Carbamazepine (Tegretol)FDA LinkGeneric
03/2012 - 03/2011
1Exenatide (Byetta)FDA Link
01/2020
1Glucagon-Like Peptide 1 (GLP 1)IBA
01/2020
1Glucagon-Like Peptide-1 Receptor AgonistsIBA
01/2020
1IncretinsIBA
01/2020
1Niacinamide (Nicotinamide)FDA LinkGeneric
01/2019
1Familial apoceruloplasmin deficiencyIBA
03/2017
1benzamideIBA
11/2016
1MMEIBA
10/2016
1coenzyme Q10 (CoQ10)IBA
08/2016
1Vitamin EFDA LinkGeneric
08/2016
1VitaminsIBA
08/2016
1Biocompatible Materials (Biomaterials)IBA
05/2016
1tributyl phosphate (TBP)IBA
09/2014
1Sodium Channels (Sodium Channel)IBA
10/2013
1Leucine (L-Leucine)FDA Link
10/2013
1HoloenzymesIBA
09/2013
1Phenytoin (Dilantin)FDA LinkGeneric
03/2012
1Lamotrigine (Lamictal)FDA LinkGeneric
03/2012
1AmifampridineIBA
08/2011
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2011
1PotassiumIBA
08/2011
1Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2011
1AminopyridinesIBA
08/2011
1Potassium Channel Blockers (Blockers, Potassium Channel)IBA
08/2011
1Shal Potassium ChannelsIBA
08/2011
1HLA-B Antigens (HLA-B)IBA
03/2011
1Nonsense Codon (Nonsense Mutation)IBA
03/2011
1PPAR gammaIBA
07/2009

Therapy/Procedure

5Activities of Daily Living (ADL)
01/2021 - 10/2014
5Therapeutics
04/2015 - 02/2008
1Exercise Therapy (Therapy, Exercise)
10/2018
1Transcranial Magnetic Stimulation
03/2014
1Spinal Manipulation
01/2014
1Physical Therapy Modalities (Physical Therapy Technique)
10/2013
1Transplantation
03/2010